To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...

To the untrained eye, the tiny spots in the tumor cell wouldn’t look like much. In fact, other scientists had noticed them in cancer before but had generally dismissed them as a mere curiosity. But to ...

Extrachromosomal circular DNA (ecDNA) represents a distinct genomic entity that exists independent of the primary chromosomal structure. In cancer, ecDNA is recognised as a potent driver of oncogene ...

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA - loops of DNA found outside of regular chromosomes - are twice as ...

Intergalactic Therapeutics has launched with $75 million in series A financing to develop a nonviral gene therapy. Most gene therapies rely on viral vectors to deliver DNA into the body, but ...

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell's own machinery to achieve its goals. In a new work appearing online Wednesday in ...

To establish chronic disease, the hepatitis B virus (HBV) must have its genome of relaxed circular DNA (rcDNA) turned into covalently closed circular DNA (cccDNA). Exactly how rcDNA becomes cccDNA has ...

Biology is no longer being hampered by the cell environment thanks to cell-free technology that makes it easier to clone DNA. Located in Tokyo, Japan, OriCiro Genomics is a pioneer in cell-free ...

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell’s own machinery to achieve its goals. In a new work appearing online Wednesday in ...

In September 1970, Janet Mertz joined the biochemistry department at Stanford University. She was one of only six new graduate students in the department and the first female one admitted in nine ...

Scientists recently captured a high-resolution video of DNA shimmying into weird shapes in order to squeeze inside cells. Now, a group of researchers in the United Kingdom has captured high-definition ...