An invaluable source of RNA, DNA, and chromatin from historical and clinical samples is formalin fixed paraffin embedded (FFPE) tissue. Globally, tissue banks, hospitals, and laboratories are ...

Formalin-fixed paraffin-embedded (FFPE) tissues have long served as invaluable resources in biomedical research, particularly in clinical and translational studies. Despite the inherent challenges ...

A prospective, non-interventional study among patients diagnosed with locally advanced or metastatic non–small-cell lung cancer to assess the adherence to oral antineoplastic therapy from data ...

Formalin-fixed paraffin-embedded (FFPE) tissues are the most widely used clinical sample types in histology and molecular diagnosis. However, due to RNA degradation and protein crosslinking, FFPE ...

As technologies and methodologies advance, so do the potential applications for biospecimens. In this article, we explore seven uses of FFPE, ranging from the common to the cutting-edge.

The primary goal of fixation is to arrest the autolysis and putrefaction of tissues with the goal of stabilizing the morphological structure and biochemical relationships between constituent proteins ...

Researchers can overcome RNA degradation challenges in preserved samples with an in situ hybridization-based single cell expression profiling assay. Scientists commonly create and archive samples as ...

Circulating tumor cells as a surrogate marker for determining response to chemotherapy in Japanese patients with metastatic colorectal cancer. Background: miRNAs have been shown to be involved in ...

Tissue/cell processing and embedding Tissue slide sectioning H&E staining Special stains including: PAS, ORO, Trichrome, VVG for elastin, Giemsa Sectioning of thick tissue curls or core punches for ...