An international team of researchers has assembled one of the largest single-cell genetic atlases ever built, profiling more ...

Definition: Gene expression is the process by which a cell turns the information in a gene into a functional product, such as an RNA molecule or a protein. In simple terms: gene expression is how a ...

Embryonic stem cells are famous for their potential, but they are equally remarkable for their restlessness. In a culture dish of seemingly identical mouse embryonic stem cells, the levels of key ...

Single-nucleus RNA sequencing captures molecular changes in the prefrontal cortex across the lifespan and in health and disease.

The ability to control gene expression across a wide range is crucial for many fields, including bioengineering, disease detection, and environmental monitoring. Research led by Lingchong You, Ph.D., ...

Researchers at the Yale School of Public Health have discovered the evolutionary rhythm of gene expression, showing that changes happen at strikingly varied rates. In the study, published in Molecular ...

Mount Sinai team tracks prefrontal cortex development and aging from infancy to 97 to reveal shared cellular pathways in ...

Functional genomics investigates these mechanisms from genetic variants to gene expression and regulation. We performed personalized functional... Aging and tissue repair involve heterogeneous ...

Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. "This is the first detailed study ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

A research team has uncovered a compact gene cluster that helps Camptotheca acuminata produce two valuable classes of specialized metabolites: camptothecin derivatives and flavonoids. By combining ...