Formulation development can involve several complex technical challenges, but an approach incorporating design of experiments can help address these difficulties. All pharmaceutical drug products are ...
Modular and podular laboratory and manufacturing allow rapid reconfiguration to support development of drugs for diverse patient populations. Merck, known as Merck, Sharp, and Dohme outside the United ...
Proteolysis-targeting chimeras (PROTACs), particularly those incorporating the von Hippel–Lindau (VHL) E3 ligase ligand, present significant physicochemical challenges due to their large molecular ...
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