Currently, mRNA display is a totally in vitro peptide or protein selection method. Owing to its unique features, we expect that this technique will be widely applied to investigate many different ...

DOMEK is a multi-step pipeline which leverages mRNA display-derived next-generation sequencing data to derive kinetic information about substrates of post-translational modification enzymes.

Objective: The development of a generalizable, fast, effective, scalable, translatable and economic purification platform is critical for the technical and economic success of mRNA-based therapeutics.

Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...

Pharmaceutical scientists at the National University of Singapore (NUS) have developed a novel chemical reaction that enables the precise functionalization of peptides and proteins. This approach ...