Akamis Bio to Present Initial Data from the Phase 1b FORTRESS Study of NG-350A in Mismatch Repair-Proficient Locally Advanced Rectal Cancer at AACR 2026 Company to disclose clinical safety and ...

Driving a car in traffic and on SF’s fabled hills takes its toll on our vehicles, and at some point, you’ll need to visit one of San Francisco’s auto repair shops. If you’re unsure where to find a ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes ...

Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas. The findings provide a clearer understanding of how these tumors develop, ...

A retrospective study found that patients with mismatch repair (MMR)-deficient advanced or recurrent endometrial cancer had numerically longer overall survival (OS) than those with MMR-proficient ...

Tecentriq plus chemotherapy reduced recurrence or death risk by 50% in stage III colorectal cancer with deficient mismatch repair. The combination therapy achieved a 3-year disease-free survival rate ...

Neoadjuvant PD-1 blockade with dostarlimab enables nonoperative management strategy for large proportion of patients. HealthDay News — A neoadjuvant programmed cell death 1 (PD-1) blockade enables ...

TUESDAY, April 29, 2025 (HealthDay News) -- A neoadjuvant programmed cell death 1 (PD-1) blockade enables nonoperative management among patients with early-stage mismatch repair-deficient (dMMR) solid ...

Among patients with mismatch repair–deficient (dMMR), locally advanced rectal cancer, neoadjuvant checkpoint blockade eliminated the need for surgery in a high proportion of patients. Whether this ...

Dostarlimab treatment led to complete clinical responses in 82% of patients with dMMR tumors, avoiding surgery for most. Recurrence-free survival at two years was 92%, with a median follow-up of 20 ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. PD-1 blockade conferred benefit to certain women with ...