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Mar 2, 2026 · In this issue of the JCI, Zhu and colleagues integrated functional genomics, single-cell transcriptomics, and analysis of human tumors to show that type I IFN signaling shapes both tumor …
JCI - About the Journal of Clinical Investigation
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JCI - Welcome
Copyright © 2026 American Society for Clinical Investigation ISSN: 0021-9738 (print), 1558-8238 (online)
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JCI is a Gold Open Access journal and deposits all published research articles in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency requirements.
JCI - Ruling in, ruling out: the clinical utility of plasma biomarkers ...
Oct 1, 2025 · Ruling in, ruling out: the clinical utility of plasma biomarkers in diagnosis of Alzheimer’s disease Julie K. Wisch and Beau M. Ances
JCI - The gut microbiome and cancer response to immune checkpoint ...
Feb 3, 2025 · The field of the microbiome and immunotherapy has skyrocketed since 2015 when two studies demonstrated a fascinating phenomenon in mice: certain gut bacteria could enhance the …
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JCI - Mechanisms and clinical implications of gut-brain interactions
Jan 2, 2026 · View this article via: JCI CrossRef PubMed Google Scholar Bauer IJ, et al. Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging.
JCI - The promise of GLP-1 receptor agonists for neurodegenerative …
Feb 16, 2026 · View this article via: JCI CrossRef PubMed Google Scholar Aviles-Olmos I, et al. Motor and cognitive advantages persist 12 months after exenatide exposure in Parkinson’s disease.
JCI - The science of safety: adverse effects of GLP-1 receptor agonists ...
Feb 16, 2026 · View this article via: JCI CrossRef PubMed Google Scholar Mentis N, et al. GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes.