PDB-101: Molecule of the Month: SARS-CoV-2 Spike
Spike protein from SARS-CoV, with one receptor binding domain (RBD) in the up position, and a closed conformation of the SARS-CoV-2 spike. The S1 fragment is shown in magenta and the S2 fragment …
5DO2: Complex structure of MERS-RBD bound with 4C2 antibody
Sep 10, 2015 · Both mAbs potently bind to MERS-RBD and block virus entry in vitro with high efficacy. We further investigated their mechanisms of neutralization by crystallizing the complex between the …
Crystal structure of SARS-CoV-2 spike receptor-binding ... - RCSB PDB
Feb 21, 2020 · Here, to better understand the initial step of infection at an atomic level, we determined the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 bound …
RCSB PDB - 8ZER: Crystal structure of the complex of Wuhan SARS …
May 6, 2024 · Here we report on the successful crystal structure determination of the RBD:P2C5 complex at 3.1 Å, which revealed the intricate protein-protein interface, sterically occluding full ACE2 …
RCSB PDB - 8Z27: The structure of TGEV RBD and dog APN complex
Apr 12, 2024 · We identified R325 of dAPN as an important residue in the PDCoV RBD-dAPN interaction, and found the central role of Q746 and T749 in dAPN in the interaction with the TGEV RBD.
RCSB PDB - 9IU1: Structure of SARS-CoV-2 JN.1 spike RBD in complex …
Jul 20, 2024 · The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the up-conformation.
RCSB PDB - 8YZD: Structure of JN.1 RBD protein in complex with ACE2.
Jan 22, 2025 · 8YZD | pdb_00008yzd Structure of JN.1 RBD protein in complex with ACE2. PDB DOI: https://doi.org/10.2210/pdb8YZD/pdb EM Map EMD-39690: EMDB EMDataResource Classification: …
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RCSB PDB - 7R6X: SARS-CoV-2 spike receptor-binding domain (RBD) in ...
Jun 23, 2021 · These data highlight principles underlying variation in escape, breadth and potency among antibodies that target the RBD, and identify epitopes and features to prioritize for therapeutic …
RCSB PDB - 8YF2: Cryo-EM structure of SARS-CoV-2 prototype RBD in ...
Feb 23, 2024 · In our study, we investigated the binding affinities of raccoon dog ACE2 (rdACE2) to the spike (S) protein receptor binding domain (RBD) of SARS-CoV-2 prototype (PT) and its variants.